Edematous severe acute malnutrition is characterized by hypomethylation of DNA

From Kwashiorkor to Edematous Malnutrition.

of the children, respectively. The frequency of vitamin A deficiency in the Kabul series (11.2%) was much lower than in the Hyderabad series (32.6%). The authors attributed this to prolonged breastfeeding, which would have helped meet the children’s vitamin A requirements. Prevalence of vitamin B complex deficiency was also lower in the Kabul series (22.2%) as compared to the Hyderabad series (...

Management of severe acute malnutrition.

Severe acute malnutrition in Asia.

Severe acute malnutrition (SAM) is a common condition that kills children and intellectually maims those who survive. Close to 20 million children under the age of 5 years suffer from SAM globally, and about 1 million of them die each year. Much of this burden takes place in Asia. Six countries in Asia together have more than 12 million children suffering from SAM: 0.6 million in Afghanistan, 0...

Severe acute malnutrition and infection

Severe acute malnutrition (SAM) is associated with increased severity of common infectious diseases, and death amongst children with SAM is almost always as a result of infection. The diagnosis and management of infection are often different in malnourished versus well-nourished children. The objectives of this brief are to outline the evidence underpinning important practical questions relatin...

Management of severe acute malnutrition in children.

Severe acute malnutrition (SAM) is defined as a weight-for-height measurement of 70% or less below the median, or three SD or more below the mean National Centre for Health Statistics reference values, the presence of bilateral pitting oedema of nutritional origin, or a mid-upper-arm circumference of less than 110 mm in children age 1-5 years. 13 million children under age 5 years have SAM, and...